Offering luggage storage, the comfortable Hotel Grifoni Venice lies in San Polo with so much to do—and buy, around 600 metres from the Large Campo San Polo Historic Square and just 1.4 km from such cultural places of interest as Querini Stampalia Foundation Fine Art Museum. Located in proximity to the wooden Academy Bridge, this smoke-free hotel features 9 rooms with views of the canal.

The hotel enjoys its convenient location approximately 5 minutes' walk from the wide Canal Grande. The Grifoni Venice is also a few steps from Museo Leonardo da Vinci, and near a train station. Guests might as well visit Giardini Papadopoli, which is 0.8 km away. Standing about a 15-minute walk away, the Roman St. Mary of Nazareth Catholic Church is a hard-to-miss divine tourist destination. For those travelling from afar, Marco Polo airport is 20 minutes' drive away.

The allergy-friendly rooms comprise a balcony and a terrace, and offer a flat-screen TV with satellite channels along with tea and coffee making equipment. Bathroom essentials include a bidet, a walk-in shower, and a separate toilet, and such comforts as hair dryers and a shower cap.

The restaurant Ristorante Rio Frari is located fairly close to Hotel Grifoni.