Orient Express Venezia Hotel features 43 rooms and lies about a 25-minute walk from the museum gallery "Gallerie dell'Accademia".

The ornate covered 16th-century stone footbridge "Rialto Bridge" is a mere 0.7 km away, while Venezia Santa Lucia train station is within reach of the hotel. Guests can visit the Casino of Venice, located only 400 m from this 5-star hotel, and the cathedral church "Basilica di San Marco", which is a 16-minute walk away. The Orient Express Venezia is not far from Libraria Aqua Alta Bookshop. There is Venezia Piazzale Roma bus stop 0.9 km from the property.

Offering Italian dishes, Osteria Antico Giardinetto lies approximately 300 metres away.