The comfortable 4-star Palazzo De Polo Hotel Venice offers proximity to San Moise, Venice, situated only 1 km away. This Venice hotel features safety facilities including a safety deposit box and 24-hour security service.

The hotel is nestled in Cannaregio, which is one of the most beautiful in the city, just 10 minutes on foot from business venues like St Mark's Clocktower and just 300 metres from the Gothic church "Basilica dei Santi Giovanni e Paolo". Chiesa di San Zulian Church stands within reach of the Palazzo De Polo Venice. The accommodation also provides access to shopping attractions like the grand showpiece square "Piazza San Marco", which are 950 metres away. This Venice hotel lies merely 1.4 km from Venezia Santa Lucia train station, and Basilica of St Mary of Health is situated nearly a 25-minute walk away.

Palazzo De Polo Hotel features 21 rooms equipped with a flat-screen TV with satellite channels as well as a mini-bar, coffee and tea making facilities. Air conditioning are featured for guests' comfort. A bidet and a separate toilet, along with hairdryers and bath sheets, are included in the private bathrooms.

Offering European meals, Antico Gatoleto is situated just around the corner from the property.